The schools announced the deal on Wednesday.
Auburn will host the game on Sept. 3, 2016. They'll meet at Clemson on Sept. 9, 2017.
The two programs have met 49 times in football starting in 1899, with Auburn holding a 34-13-2 advantage. They haven't met since 2012 when Clemson won the opener 26-19 in Atlanta.
This will mark the seventh time in eight seasons that Clemson will play two Southeastern Conference teams. Clemson plays rival South Carolina to end each season.
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