The Greyhounds defeated Hillgrove by a score of 63-9 to claim the title, while Kennesaw Mountain topped Kell 55-22 in the third-place match.
"This was our third event so far this season, and I like what I'm seeing," Pope coach Jim Haskin said. "The guys are working on a lot of technique and conditioning, and it's going well. If their matches happen to go to the third period, then they're winning in the third, which is what you want.
"We maybe lost only five or six matches on the day, and a bunch of guys went undefeated. That's great to see, no matter what tournament you're in, but for now, we're going to take it an event at a time. All along, I've wanted to see progress, and we're seeing that with these young kids."
Pope quickly jumped out to a 42-0 lead over Hillgrove as Patrick Anthony (160 pounds), Trevor Stevens (189), Curran McMahon (215), Cameron Munsey (112) and Tucker Coltek (119) all picked up pins.
Danny Litton (285) won via forfeit, while Joey Tabaccino (171) and Tyler Haskin (103) each won by decision.
Russell Scott-Peel put Hillgrove in the win column following a decision victory at 125. Pope's Louis Lombordy won a decision at 130 to extend the Greyhounds' advantage, and Derek Davis' pin at 135 gave them a 51-3 margin.
Garrett Johnson added to Hillgrove's total with a pin at 3:43, which was followed by back-to-back pins from Pope's Garrett Swartz (145) and Jake Henson for the 63-9 win.
"This is our fourth year of the Duals, and it's the first time we've finished runner-up," Hillgrove coach Luke McSorley said. "We were third last year, so this is good. We knew we had a good team heading into the season. We beat Kennesaw Mountain and McEachern, so that's big in terms of region criteria.
"We went 4-1 (Tuesday), and it's a big confidence-boost to start the season with big wins. The kids feed off that and, hopefully, it will carry over."
Pope won its pool with lopsided wins over Lassiter (59-6), North Cobb (84-0), Woodstock (75-6) and Kell (69-6).
Hillgrove also went 4-0 in its pool with wins over McEachern (42-27), Kennesaw Mountain (42-36), Walton (42-18) and Sprayberry (44-22).
The Mustangs, who went 3-1 in their pool and 4-1 overall, were first-time participants in the Hillgrove Duals.
"We definitely wanted to be in the finals, and thought we had a chance to do that," Kennesaw Mountain coach Roberto Rivera said. "We have six brand-new wrestlers who wrestled in matches for the first time (Tuesday), and I thought they wrestled tough.
"We had some guys out, but we'll get our lineups situated as the season goes on."
Kell finished 3-1 in its pool and 3-2 overall. McEachern and Lassiter each went 2-2, Sprayberry and North Cobb were each 1-3 and Walton and Woodstock were 0-4.