None of the more than 1,700 Africans sickened by Ebola have received this treatment.
This drug, "ZMapp," is so novel and unproven that not much is available and its effectiveness remains unknown. It could end up doing more harm than good. It would take months to produce the drug in any modest quantity, and even then, using it more widely would present other ethical dilemmas.
But many Africans are seeing a larger, bitter truth in the fact that two Americans and a Spaniard were able to get this treatment after being infected in West Africa, where the hemorrhagic fever has raged for months.
"There's no reason to try this medicine on sick white people and to ignore blacks," said Marcel Guilavogui, a pharmacist in Conakry, Guinea. "We understand that it's a drug that's being tested for the first time and that could have negative side effects. But we have to try it in blacks too."
The ethical questions posed by this situation have been so difficult that the U.N. health agency organized a teleconference Monday between about a dozen ethicists, infectious disease experts and patient representatives, including people from universities and the Doctors Without Borders group. Most of the participants are from developed countries, but Uganda and Senegal had people in the meeting.
The World Health Organization said it would hold a news conference Tuesday, but didn't announce whether it would make recommendations for which Ebola patients should get experimental therapies, and how.
"It certainly looks bad that only three Westerners have gotten the drug while most of the people with Ebola are African," said Art Caplan, director of bioethics at NYU Langone Medical Center.
The drugmaker should make its policy for distributing its treatment clear, said Caplan, who did not participate in the WHO teleconference. "I don't think this scarce resource should just be given to whoever is best connected."
The drug is made by Mapp Biopharmaceutical Inc., a small, San Diego-based company that did not respond to calls or emails from The Associated Press on Monday.
Companies can provide experimental drugs on a "compassionate use" basis, usually after they have been fully tested. In the US, such use must be approved by the Food and Drug Administration, but the FDA has no authority overseas. It is up to the company whether they want to share their drug.
Spain's Health Ministry said it obtained ZMapp this weekend with company permission to treat Miguel Pajares, a 75-year-old priest evacuated from Liberia and placed in isolation Thursday at Madrid's Carlos III Hospital.
The ministry said "the medicine was imported from Geneva where there was one dose available in the context of an accord between the laboratory that developed the medicine, WHO and (Doctors Without Borders)."
The ministry also said it invoked a Spanish law permitting unauthorized medication for patients with a life-threatening illness who cannot be treated satisfactorily by authorized drugs.
Spanish authorities refused to comment beyond the ministry's statement, but Geneva University Hospital told The Associated Press it was involved in getting the drug to Madrid.
The evacuated Americans, Dr. Kent Brantly and Nancy Writebol, have been improving at Atlanta's Emory University Hospital. They got the treatment after Samaritan's Purse asked the drug's manufacturer, Kentucky BioProcessing, which is producing the drug for Mapp Biopharmaceutical.
Mapp Pharmaceutical says on its website that "very little of the drug is currently available" and that it is working with government agencies to increase production as quickly as possible.
The treatment is a mixture of three antibodies engineered to recognize Ebola and bind to infected cells so the immune system can kill them.
Absent a known cure or licensed treatment, Ebola has killed more than 960 people since it emerged in Guinea in March and spread to Liberia, Sierra Leone and possibly Nigeria.
Nigeria's health minister, Onyenbuchi Chukwu, said last week that when he asked the U.S. Centers for Disease Control and Prevention about getting the drug, he was told the manufacturer would have to agree and that the CDC would not be involved. Guinea said Monday it too would like to have some of the drug.
"Guinean authorities would naturally be interested in having this medicine," said Alhoussein Makanera Kake, spokesman for the government committee fighting Ebola.
In Nigeria, where local officials say they have 10 confirmed cases, people are already sending tweets demanding the drug. WHO has publicly noted the Nigerian caseload, but has yet to confirm Ebola's spread there.
In other Ebola developments Monday:
— A Catholic humanitarian group based in Spain said another religious worker and colleague of the infected Spanish priest had died in from Ebola in Liberia.
— Nigerian health authorities confirmed another Ebola case Monday, a nurse who treated Patrick Sawyer, the Liberian-American who flew into Nigeria and died last month. That brings Nigeria's locally confirmed Ebola cases to 10, including the two who died, Sawyer and another nurse. Nigeria also is monitoring 177 contacts of Sawyer.
— Liberia announced that a donation of protective gear from China was arriving Monday. A shortage of full-body suits and even clean surgical gloves has left health workers exposed to the virus and prompted some to refuse to treat Ebola patients.
— George Weah, a former FIFA world player of the year from Liberia, has joined the efforts to spread awareness about the disease and how to prevent it. He recorded a song titled "Ebola is real," and proceeds are going to the Liberian Health Ministry.
Medical writer Cheng reported from London. AP writers Jonathan Paye-Layleh from Monrovia, Liberia, Boubacar Diallo in Gonakry, Guinea and Bashir Adigun from Abuja, Nigeria, also contributed to this report.
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